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  Pharmacokinetics of a two mg eszopiclone dose ended up assessed in 16 healthier volunteers As well as in 8 topics with mild, reasonable, and extreme liver condition. Exposure was enhanced 2-fold in severely impaired sufferers as opposed Along with the nutritious volunteers. Cmax and tmax ended up unchanged. No dose adjustment is essential for cl

  Pharmacokinetics of the 2 mg eszopiclone dose had been assessed in 16 healthy volunteers and in 8 subjects with gentle, moderate, and significant liver ailment. Exposure was greater 2-fold in severely impaired people in comparison With all the healthier volunteers. Cmax and tmax were unchanged. No dose adjustment is necessary for individuals wit